All of Us Research Program

Creating the right health approaches and care for the right person is called precision medicine. Precision medicine is an approach to disease prevention and treatment that takes into account individual variability in genes, environment and lifestyle to aid in the development of individualized care. Getting the right information to make that happen is the goal of the All of Us Research Program from the National Institutes of Health (NIH).

To get there, we want to create the largest health database ever. By understanding people's health, neighborhood, family, and lifestyle, researchers will have information to better understand health and disease. This information is essential to create a healthier future for generations to come.

Join the All of Us Research Program

Why Should I Join?

If you join, you will be contributing to research that may improve health for everyone. Our goal is to understand what makes people sick and to develop new treatments. Here are some examples of what researchers might be able to discover from their research:

  • Better tests to see if people are sick or are at risk of getting sick.
  • Better mobile apps to encourage healthy habits.
  • Better medicine or information about how much of a medicine is right for each person as an individual.

Also, you will be able to see your information, which might be interesting to you. You may also learn about your health. If you choose, you will be able to share your information with your doctor.

Frequently Asked Questions

What do I need to do to join?

The All of Us Research Program began NYC enrollments in 2017. There are three ways to join:

Because All of Us is a research program, you will be asked to complete an informed consent process. This process tells more about what is involved, and the risks and benefits of joining.

Can anyone sign up?

Yes, anyone living in the United States will be able to participate, though enrollment will initially be limited to adults ages 18 years and up. Certain populations, such as children, will be included at a later time.

How much of my time will be required to fully participate?

The consent forms and health surveys may take about 30-45 minutes to complete. You can complete the consents and surveys online before your in-person visit at one of our enrollment centers. At the in-person visit you will be asked to provide physical measurements and biospecimens (blood and urine), which will take an additional 30 minutes. If you prefer to complete all enrollment activities at your in-person appointment, please leave adequate time to do so

Is joining a one-time activity or ongoing?

The All of Us Research Program will last at least 10 years. You will receive updates from the National Institutes of Health . We hope you will stay involved over time. If you do, researchers may better understand what causes changes in our health and what we can do about it.

What will the All of Us Research Program ask of me as a participant over time?

If you decide to join, we will ask you to share different kinds of information. We will ask you basic information like your name and where you live. We will ask you questions about your health, family, home, and work. If you have an electronic health record, we will ask for access. We will ask you to go to a local New York City Consortium enrollment center. At this appointment we will measure your weight, height, hips, and waist, as well as your blood pressure and heart rate. We will ask you to provide blood and urine samples.

We may contact you to answer additional surveys from time to time. You can choose to answer the surveys or not. We may also contact you periodically to ensure that your contact information is up-to-date in our system.

What do we hope to learn?

The All of Us Research Program will build one of the world’s largest and most diverse data sets for precision health research. With data from one million or more participants who contribute information over a long period of time, researchers may be able to:

  • Develop ways to measure risk for a range of diseases based on environmental exposures, genetic factors, and interactions between the two;
  • Identify the causes of individual differences in response to commonly used drugs (commonly referred to as pharmacogenomics);
  • Discover biological markers that signal increased or decreased risk of developing common diseases;
  • Use mobile health technologies to correlate activity, physiological measures, and environmental exposures with health outcomes;
  • Develop new disease classifications and relationships;
  • Empower study participants with data and information to improve their own health; and create a platform to enable trials of targeted therapies.

As the program develops, NIH will hold additional workshops to discuss scientific opportunities in more detail and chart future directions.

Which diseases will be studied?

This large-scale cohort will not be focused on a specific disease, but instead will be a broad resource for researchers working on a variety of important health questions. Researchers have already seen successful precision medicine approaches in treating certain types of cancers. This cohort will seek to extend that success to many other diseases, including common diseases such as diabetes, heart disease, Alzheimer’s, obesity, and mental illnesses, as well as rare diseases. Importantly, the cohort will focus not just on disease, but also on ways to increase an individual’s chances of remaining healthy throughout their life.

How long before we see the results of precision medicine in the form or new treatments or preventions?

Precision medicine is an approach to disease prevention and treatment that takes into account individual variability in genes, environment and lifestyle to aid in the development of individualized care. This is not a new area of science. While we have seen some great progress, it can take many years to understand the contribution of a single unique variable on a given disease or treatment. It will take even more time to develop new treatments and methods of disease prevention. By launching a study of the size and scope proposed here, we hope to accelerate our understanding of disease onset and progression, treatment response, and health outcomes.

How will you protect my information?

We will take great care to protect your information. Here are a few of the steps we will take:

  • Information we have about you will be stored on protected computers. We will limit and keep track of who sees the information.
  • We will remove your name and other direct identifiers (like your date of birth) from your information and replace them with a code. There will be a master list linking the codes to names, but we will keep it separate and secure.
  • In order to work with your health information, researchers will promise not to try to find out who you are.
  • We will tell you if there is a data breach.
  • The All of Us Research Program has Certificates of Confidentiality from the U.S. government. This will help us fight legal demands (such as a court order) to give out information that could identify you.

Who We Are

Weill Cornell Medicine is one of the top academic medical centers in the country, with a history of excellence in patient care, scientific discovery, and the education of future physicians and healthcare leaders. Learn more about Weill Cornell Medicine >>

Weill Cornell Medicine is part of the New York City Precision Medicine Consortium, a partner of the All of Us Research Program. In addition to Weill Cornell Medicine, the consortium includes Columbia University Medical Center, NYC Health + Hospitals Harlem, and NewYork-Presbyterian. All of Us is part of the National Institutes of Health.

Contact Us

Have a comment or questions? We’d love to hear from you. Contact us online by using this form or by calling (646) 962-6170.