Research & Collaboration

The primary mission of the Department is to conduct research and evaluations that pushes forward evidence to maximize the value of healthcare. Across the divisions, our research and evaluations address questions of the cost-effectiveness, and comparative effectiveness of various health care interventions and delivery models. Faculty members conduct research to improve healthcare delivery in this country and around the world. The department also collaborates with colleagues to develop and evaluate programs to improve healthcare.

Our research portfolio has undergone exponential growth, including a significant increase in funding from the National Institutes of Health (NIH). Our faculty members have substantial research strengths across a variety of areas including health policy and economics, health data science and data analytics, health informatics, comparative effectiveness & outcomes research, healthcare delivery science, and biostatistics. 

Research highlights include:

  • Utilizing advanced computational techniques to identify Parkinson’s disease subtypes and guide treatment
  • Developing algorithms for identifying and predicting patients with modifiable high use of healthcare
  • Leading a multi-institutional research center (CHERISH) focused on developing and disseminating health economic research related to HIV, HCV, and Substance User Disorder
  • Building a national medical device evaluation system (MDEpiNet)
  • Conducting clinical trials comparing existing methods of care against new therapy approaches for treating breast cancer
  • Constructing a learning healthcare system for pediatric epilepsy
  • Improving decision making in prescription of medications to treat diabetes through patient-centered outcomes research

Divisions & Institutes

Biostatistics and Epidemiology

The Division supports design and analysis of clinical and translational research at the medical college and serves as an academic home for biostatistics and epidemiology.

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Comparative Effectiveness & Outcomes Research

This Division pursues comparative effectiveness and outcomes research related to medications, medical devices, procedures and healthcare delivery interventions.

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Health Informatics

This Division develops novel informatics and health IT methods and tools, and studies their application in the intelligent use of healthcare data to inform policy and decision making.

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Health Policy & Economics

This Division focuses on organization, payment methods and processes used to improve the U.S. healthcare system and medical care.

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Healthcare Delivery Science & Innovation

The Division of Healthcare Delivery Science and Innovation will enhance the health system at the micro level to improve care in the real world. This division will focus on the development, implementation and evaluation of patient-centered clinical innovations.

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Disease & Disaster Preparedness

Weill Cornell Medicine (WCM) Disease & Disaster Preparedness staff have helped pioneer quantitative public health planning following 9/11, leveraging affiliated scientific disciplines such as operations research to gather information for policies that are now integral to health protection strategies in the U.S. and abroad.

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Health Technologies & Interventions

Health Technologies & Interventions staff initiate, conduct and share outcome and quality-of-care research within the context of interventional medicine and devices. Utilizing the WCM and NewYork-Presbyterian hospital network for their studies, they generate new medical technology and clinical strategy knowledge and improve our quality and efficiency of care.

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Research Programs

All of Us

The All of Us Research Program is a historic effort to collect data from one million or more people living in the United States to accelerate research and improve health, building one of the largest health databases. By taking into account individual differences in lifestyle, environment, and biology, researchers will develop precise medicine and treatment paths catered to you. This is a collaborative consortium project in partnership with NewYork-Presbyterian, Columbia University Medical Center, and Harlem Hospital.

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INSIGHT Clinical Research Network

INSIGHT Clinical Research Network, formerly known as the NYC-CDRN, offers users a large volume of robust, high-quality patient data including clinical, claims and social determinant data, along with support services to improve and streamline research in an effort to advance patient-centered research in New York City. INSIGHT has data on over 22 million patients, with 12 million unique patients eligible for trial enrollment. The project is a unique collaboration of more than 20 medical institutions and organizations. INSIGHT is currently funded by the Patient-Centered Outcomes Research Institute (PCORI).

CHERISH

The Center for Health Economics of Treatment Interventions for Substance Use Disorders, HCV, and HIV (CHERISH) is a multi-institutional Center of Excellence, funded by the National Institute on Drug Abuse. The Center’s mission is to develop and disseminate health economic research on healthcare utilization, health outcomes and health-related behaviors that informs substance use disorder treatment policy and HCV and HIV care of people who use substances. To increase the impact of this research, we support researchers in addressing the needs of integrated healthcare system providers and payers. The Center is a collaboration among Weill Cornell MedicineBoston Medical Center, the University of Pennsylvania, and the University of Miami Miller School of Medicine.

MDEpiNet

The Medical Device Epidemiology Network (MDEpiNet) is a global Public-Private Partnership that brings together leadership, expertise and resources from health care professionals, industry, patient groups, payers, academia and government to build a national patient-centered medical device evaluation system to conduct medical device research and surveillance. MDEpiNet’s main activities include:

  1. Conducting studies to better understand how devices perform in the real-world.
  2. Developing methodologies to support the use and creation of real world evidence.
  3. Building strategically Coordinated Registry Networks (CRN) to advance the collection and use of real-world data.
  4. Collaborating with NESTcc to link CRNs with other data partner networks.

 MDEpiNet envisions a future with more efficient medical device studies and greater patient, clinician and public trust in medical devices.

Center for the Study of Physician Practice and Leadership

The goal of The Physicians Foundation Center for the Study of Physician Practice and Leadership (CPPL) is to help create conditions that enable physicians – and the organizations where they work – to improve the health of individual patients and of the U.S. population while helping to constrain the growth of health care costs.  The Center pursues this goal by conducting and disseminating empirical research and by writing conceptual articles aimed at clarifying key issues and at informing public policies as well as the private policies created by health care organizations.

CPPL is particularly interested in the health of disadvantaged populations, in intended and unintended consequences of financial and nonfinancial incentives for physicians and provider organizations, in issues related to the acquisition and consolidation of provider organizations, in outpatient care, in post-acute care, in public and private policies likely to support physician professionalism, in physician leadership, and in comparative effectiveness research on the health care delivery system: what types of organizations, given what types of incentives, are most likely to improve the health of their population of patients?

The Center is made possible by a grant from The Physicians Foundation, a non-profit organization seeking to empower physicians to lead in the delivery of high-quality, cost-efficient healthcare, and contributions by Weill Cornell Medicine, one of the top-ranked clinical and medical research centers in the U.S.

Pediatric Epilepsy Learning Health System

Pediatric Epilepsy Learning Health System (PELHS) collects administrative and clinical data entered at the point of care, aggregates and analyzes the data across multiple sites, then regularly reports findings back to sites to continuously improve care. Due to the large number of individuals with epilepsy, the heterogeneity of the epilepsies, and the diversity of advocacy groups for common and rare epilepsies, PELHS offers novel opportunities to the LHS design.  

PELHS Areas of Improvement

Seizure Control
Increase the percentage of epilepsy visits in which seizure frequency and severity is documented, as well as the percentage of patients who have met their goal for seizure reduction and seizure freedom.
Patient Activation and Quality of Life
Identify aspects of care and outcomes that most influence patient and caregiver sense of well-being and integrate these ideas seamlessly in all our work.
Screening and Treatment of Depression and Anxiety
Develop systems to identify and treat depression and anxiety for all patients in the network.
Patient Transition from Pediatric to Adult Care
Increase the number of people who receive evidence-based management of transition of care.
Counseling on Contraception and Pregnancy
Increase the percent of patients who receive appropriate counseling on contraception and pregnancy planning, ultimately decreasing the percentage of unplanned pregnancies in women with epilepsy and ensuring appropriate care in all pregnant women with epilepsy.
Status Epilepticus
Prevent and terminate status epilepticus by deploying interventions that reduce the time from recognition of seizure to management.

Community Engagement

The PELHS Community Engagement Core offers ways for patients  and families to get involved as partners to advance care and support,  participate on the center improvement teams and provide patient perspective for “co-production.” The Community Engagement Core is built on partnerships with local Epilepsy Foundation and Rare Epilepsy Network organizations for priority-setting, community-based support, wellness and self-management tools.

Healthcare Policy & Research 402 E. 67th St. New York, NY 10065 Phone: (646) 962-8001